副教授
地址:南京大学环境学院B519室
电话:
Email: hongboli@nju.edu.cn
教育经历
2007.09–2012.12 | 中国科学院 | 城市环境研究所 | 博士 |
2003.09–2007.07 | 北京师范大学 | 环境学院 | 学士 |
工作经历
2020.06–至今 | 南京大学 | 环境学院 | 博导 |
2016.11–至今 | 南京大学 | 环境学院 | 副教授 |
2015.01–2016.10 | 南京大学 | 环境学院 | 副研究员 |
2013.01–2014.12 | 南京大学 | 环境学院 | 博士后 |
研究领域
多途径暴露重金属的人体生物有效性及其调控机制,旨在揭示控制重金属人体内暴露的关键环节-人体生物有效性的影响因素及作用机制,构建和完善基于人体生物有效性的环境暴露和健康风险评估体系,力图通过对重金属人体生物有效性的调控,达到对人群重金属暴露风险的科学防控。
学术兼职
国际环境类期刊Chemosphere编委
Bulletin of Environmental Contamination and Toxicology期刊专刊客座编辑。
课程教学
《化学实验基础》
《环境化学实验》
科研项目
国家自然科学基金优秀青年科学基金项目,42022058,基于人体生物有效性的重金属暴露评估与调控,2021-01至2023-12,120万元,在研,主持
江苏农业科技自主创新资金项目,CX(21)3095,降低稻米和小麦籽粒中镉人体生物有效性的农艺和膳食调控技术研发,2021-07至2023-06,30万元,在研,主持
国家自然科学基金面上项目,41877356,稻米中镉的人体生物有效性及调控机制研究,2019-01至2022-12, 62 万,在研, 主持
国家重点研发计划 (科技部 ) 项目,2018YFC1801004,项目 场地土壤污染物形态原位表征和生物有效性的标准化测试方法研究 课题 场地土壤典型污染物人体生物有效性标准测试方法的建立 子课题"场地土壤典型重金属人体生物有效性测试方法开发", 2018-12至2022-11, 76 万,在研, 主持
国家自然科学基金重点项目,21637002,土壤–水稻体系中砷迁移与阻控及其健康风险研究,2017-01至2021-12,291万元,在研,项目骨干
国家重点研发计划(科技部)项目,2016YFD0800807,设施农业镉砷污染土壤的植物高效萃取修复技术体系研究与示范子课题"土壤砷中轻度污染植物萃取修复技术与集成",2016-01至2020-12, 50万元, 已结题, 主持
国家自然科学基金青年项目,21507057,典型污染区室内灰尘中铅砷人体生物有效性预测模型的构建与应用, 2016-01至2018-12, 24万元, 已结题,主持
江苏省自然科学基金青年项目,BK20150573,基于人体胃肠模拟液体外法的典型污染区室内灰尘中铅砷的生物有效性及人体健康风险研究, 2015-07至2018-06,20万元,已结题,主持
江苏省博士后基金A类项目,1301006A,基于同步辐射X射线和Pb稳定同位素比例技术的中国室内灰尘Pb形态、来源及人体生物可利用性研究,2013-07至2014-12,6万元,已结题,主持
代表性论文
Li MY, Chen XQ, Wang JY, Wang HT, Xue XM, Ding J, Juhasz AL, Zhu YG, Li HB*, Ma LQ*. Antibiotic exposure decreases soil arsenic oral bioavailability in mice by disrupting ileal microbiota and metabolic profile. Environment International, 2021, 151, 106444.
Hong-Bo Li*, Han Ning, Shi-Wei Li, Jie Li, Rong-Yue Xue, Meng-Ya Li, Meng-Yu Wang, Jia-Hui Liang, Albert L. Juhasz, and Lena Q. Ma*. An interlaboratory evaluation of the variability in arsenic and lead relative bioavailability when assessed using a mouse bioassay. Journal of Toxicology and Environmental Health, Part A: Current Issues. 2021, DOI: 10.1080/15287394.2021.1919947.
Li HB*, Wang JY, Chen XQ, Li YP, Fan J, Ren JH, Luo XS, Juhasz AL, Ma LQ. Geogenic nickel exposure from food consumption and soil ingestion: A bioavailability based assessment. Environmental Pollution 265 (2020) 114873.
Li HB*, Li MY, Zhao D, Li J, Li SW, Xiang P, Juhasz AL, Ma, LQ*. Arsenic, lead, and cadmium bioaccessibility in contaminated soils: Measurements and validations. Critical Reviews in Environmental Science and Technology. 2020, 50, 13, 1303-1338.
Yangyang Wu, Jianing Lou, Xue Sun, Lena Q. Ma, Jueyang Wang, Mengya Li, Hong Sun, Hongbo Li*, Lei Huang*. Linking elevated blood lead level in urban school-aged children with bioaccessible lead in neighborhood soil. Environmental Pollution, 2020, 261, 114093.
Zhao D, Wang JY, Yin, DX, Li MY, Chen XQ, Juhasz AL, Luo J, Navas-Acien A, Li, HB*, Ma LQ. Arsanilic acid contributes more to total arsenic than roxarsone in chicken meat from Chinese markets. Journal of Hazardous Materials 2020, 383, 121178.
Kaihong Yan, Zhaomin Dong, Ravi Naidu*, Yanju Liu, Yeling Li, Ayanka Wijayawardena, Peter Sanderson, Hongbo Li*, Lena Q. Ma. Comparison of in vitro models in a mice model and investigation of the changes in Pb speciation during Pb bioavailability assessments. Journal of Hazardous Materials 2020, 388, 121744.
Li HB*, Chen XQ, Wang JY, Li MY, Zhao D, Luo XS, Juhasz AL, Ma, LQ. Antagonistic interactions between arsenic, lead, and cadmium in the mouse gastrointestinal tract and their influences on metal relative bioavailability in contaminated soils. Environmental Science & Technology, 2019, 53, 14264−14272.
Li HB*, Li MY, Zhao D, Li J, Li SW, Juhasz AL, Basta NT, Luo YM, Ma, LQ*. Oral bioavailability of As, Pb, and Cd in contaminated soils, dust, and foods based on animal bioassays: a review. Environmental Science & Technology, 2019, 53, 10545−10559.
Zhu X, Li MY, Chen XQ, Wang JY, Li LZ, Tu C, Luo YM*, Li, H.B.*, Ma, L.Q. As, Cd, and Pb relative bioavailability in contaminated soils: coupling mouse bioassay with UBM assay. Environment International, 2019, 130, 104875.
Li MY, Wang P, Wang JY, Chen XQ, Zhao D, Yin DX, Luo J, Juhasz AL, Li, H.B.*, Ma, L.Q*. Arsenic concentrations, speciation, and localization in 141 cultivated market mushrooms: implications for arsenic exposure to humans. Environmental Science & Technology, 2019, 53, 503−511.
Zhao, D., Wang, J. Y., Tang, N., Yin, D.X., Luo, J., Juhasz A.L., Xiang, P., Li, H.B.*, Ma, L.Q*. Coupling bioavailability and stable isotope ratio to discern dietary and non-dietary contribution of metal exposure to residents in mining-impacted areas. Environment International 2018, 120, 563–571.
Zhao, D., Juhasz, A. L., Luo, J., Li H. B.*, Ma, L. Q. Metals in paints on chopsticks: Solubilization in simulated saliva, gastric, and food solutions and implication for human health. Environmental Research 2018, 167, 299–306.
Li H. B., Li, M. Y., Zhao D, Zhu Y. G., Li, J., Juhasz, A. L., Cui, X. Y., Luo J., Ma L. Q*. Food influence on lead relative bioavailability in contaminated soils: mechanisms and health implications. Journal of Hazardous Materials 2018, 358, 427–433.
Wang, N, Yu, J. G*, Zhao, Y. H., Chang, Z. Z., Shi, X. X., Ma, L. Q., Li, H. B.*. Straw enhanced CO2 and CH4 but decreased N2O emissions from flooded paddy soils: Changes in microbial community compositions. Atmospheric Environment 2018, 174: 171–179.
Zhao, D., Juhasz, A. L., Luo, J., Huang, L., Luo, X.S., Li, H. B.*; Ma, L. Q.*, Mineral dietary supplement to decrease cadmium relative bioavailability in rice based on a mouse bioassay. Environmental Science & Technology 2017, 51, 12123−12130.
Sun, H. J.#, Li, S. W.#, Li, C., Wang, W. Q., Li, H. B.*, Ma, L. Q. Thyrotoxicity of arsenate and arsenite on juvenile mice at organism, subcellular, and gene levels under low exposure. Chemosphere 2017, 186, 580−587.
Li, S. W., Liu, X., Sun, H. J., Li, M. Y., Zhao, D., Luo, J. , Li, H. B.*, L. Q. Ma. Effect of phosphate amendment on relative bioavailability and bioaccessibility of lead and arsenic in contaminated soils. Journal of Hazardous Materials 2017, 339, 256–263.
Zhao, D., Liu, R. Y., Xiang, P., Juhasz, A. L., Huang, L., Luo, J., Li, H. B.*, Ma, L. Q. Applying cadmium relative bioavailability to assess dietary intake from rice to predict cadmium urinary excretion in nonsmokers. Environmental Science & Technology 2017, 51, 6756–6764.
Hongbo Li, X. Dong, E. B. da Silva, L. M. de Oliveira, Y. Chen*, and L. Q. Ma*. Mechanisms of metal sorption by biochars: Biochar characteristics and modifications. Chemosphere 2017, 178, 466–478.
Li H. B., Li, J., Zhao, D., Li, C., Wang, X. J., Sun, H. J., Juhasz, A. L., Ma, L. Q.*. Arsenic relative bioavailability in rice using a mouse arsenic urinary excretion bioassay and its application to assess human health risk. Environmental Science & Technology, 2017, 51, 4689−4696.
Wang, N., Z. Z. Chang*, X. X. Xue, J. G. Yu, X. X., Shi, L. Q. Ma, and Hongbo Li*. Biochar decreases nitrogen oxide and enhances methane emissions via altering microbial community composition of anaerobic paddy soil. Sci Total Environ 2017, 581–582, 689–696.
Li, S. W., Sun, H. J., Wang, G., Cui, X. Y., Juhasz, A. L., Li, H. B.*, Ma, L. Q. *. Lead relative bioavailability in soils based on different endpoints of a mouse model. Journal of Hazardous Materials 2017, 326, 94–100.
Wang, N., X. M. Xue, A. L. Juhasz, Z. Z. Chang*, and Hongbo Li*. Biochar increases arsenic release from an anaerobic paddy soil due to enhanced microbial reduction of iron and arsenic. Environ Pollut 2017, 220, 514–522.
Sun, H. J., P. Xiang, J. Luo, H. C. Hong, H. J. Lin, Hongbo Li*, and L. Q. Ma*. Mechanisms of arsenic disruption on gonadal, adrenal and thyroid endocrine systems in humans: A review. Environ Int 2016, 95, 61–68.
Li H. B., Zhao, D., Li, J., Li, S. W., Wang, N., Juhasz, A. L., Zhu, Y. G., Ma, L.Q.*. Using the SBRC assay to predict lead relative bioavailability in urban soils: contaminant source and correlation model. Environmental Science & Technology 2016, 50, 4989–4996.
Di, Zhao, Jie Li, Chao Li, Albert L. Juhasz, Kirk G. Scheckel, Jun Luo, Hongbo Li*, Lena Q. Ma*. Lead relative bioavailability in lip products and their potential health risk to women. Environmental Science & Technology 2016, 50, 6036–6043.
Li, J., Li, C., Sun. H. J., Juhasz, A. L., Luo J., Li, H. B.*, Ma, L.Q.*. Arsenic relative bioavailability in contaminated soils: Comparison of animal models, dosing schemes and biological endpoints. Environmental Science & Technology 2016, 50, 453–461.
Jun Ma#, Yi Liu#, Guangbin Yu#, Hongbo Li#, Shen Yu*, Yueping Jiang, Guilin Li, Jinchang Lin. Temporal dynamics of urbanization-driven environmental changes explored by metal contamination in surface sediments in a restoring urban wetland park, J Hazard Mater 2016, 309, 228-235.
Hongbo Li, Kai Chen, Albert L. Juhasz, Lei Huang*, Lena Q. Ma*. Childhood lead exposure in an industrial town in China: coupling stable isotope ratios with bioaccessible lead. Environmental Science & Technology 2015, 49, 5080-5087.
Hongbo Li, Jie Li, Yaguang Zhu, Albert L. Juhasz, Lena Q. Ma*. Comparison of arsenic bioaccessibility in housedust and contaminated soils based on four in vitro assays. Sci Total Environ 2015, 532, 803-811.
Jie Li, Kan Li, Mark Cave, Hongbo Li*, Lena Q. Ma*. Lead bioaccessibility in 12 contaminated soils from China: Correlation to lead relative bioavailability and lead in different fractions. J Hazard Mater 2015, 295, 55–62.
Jie Li, Kan Li, Xinyi Cui, Nicholas T. Basta, Liping. Li, Hongbo Li*, Lena Q. Ma*. In vitro bioaccessibility and in vivo relative bioavailability in 12 contaminated soils: Method comparison and method development. Sci Total Environ 2015, 532, 812–820.
Hongbo Li, Jie Li, Albert L. Juhasz, Lena Q. Ma*. Correlation of in vivo relative bioavailability to in vitro bioaccessibility for arsenic in household dust from China and its implication for human exposure assessment. Environmental Science & Technology 2014, 48, 13652–13659.
Hongbo Li, Xinyi Cui, Kan Li, Jie Li, Albert L. Juhasz, Lena Q. Ma*. Assessment of in vitro lead bioaccessibility in house dust and its relationship to in vivo lead relative bioavailability. Environmental Science & Technology 2014, 48, 8548–8555.
Hongbo Li, Shen Yu*, Guilin Li, Hong Deng, Bo Xu, Jing Ding, Jingbo Gao, Youwei Hong, Minghung Wong. Spatial distribution and historical records of mercury sedimentation in urban lakes under urbanization impacts. Sci Total Environ 2013, 445–446, 117–125.
Hongbo Li, Shen Yu*, Guilin Li, Hong Deng. Lead contamination and source in Shanghai in the past century using dated sediment cores from urban park lakes. Chemosphere 2012, 88, 1161–1169.
Hongbo Li, Shen Yu*, Guilin Li, Yi Liu, Guangbin Yu, Hong Deng, Shengchun Wu, Minghung Wong. Urbanization increased metal levels in lake surface sediment and catchment topsoil of waterscape parks. Sci Total Environ 2012, 432, 202–209.
Hongbo Li, Shen Yu*, Guilin Li, Hong Deng, Xiaosan Luo. Contamination and source differentiation of Pb in park soils along an urbanization gradient in Shanghai. Environ Pollut 2011, 159, 3536–3544.
宁涵, 王梦雨, 历红波*. 钝化剂对土壤砷、铅、镉的人体生物有效性的影响研究. 生态毒理学报. 2021. 已录用
林欣颖, 谭祎, 历红波*. 稻米镉积累的影响因素与阻控措施. 环境化学, 2020, 39, 1530-1543.
王珏旸, 林欣颖, 宋维昊, 陈笑强, 李梦雅, 王宁, 历红波*. 市售面粉及面制品中镉的人体健康风险研究[J]. 环境化学, 2019, 38(6): 1232-1240
学术专著
无
授权发明专利
王珏旸, 历红波. 一种测定土壤和食品中镍的小鼠生物有效性的方法. 专利号: ZL 2019 1 1245086.3. 申请日: 2019年12月6日. 授权公告日: 2020年12月15日.
科技奖励
无
招生情况
博士毕业生(3名) | 毕业年份 | 工作单位 |
李洁 | 2016 | 山东师范大学地理与环境学院 |
李士伟 | 2017 | 济南大学水利与环境学院 |
赵迪 | 2019 | 南京农业大学资源与环境科学学院 |
硕士毕业生(4名) | 毕业年份 | 工作/学习单位 |
王珏旸 | 2020 | 常熟市水务局 |
陈笑强 | 2020 | 安徽省生态环境厅 |
宁涵 | 2021 | 杭州市滨江区浦沿街道 |
王梦雨 | 2021 | 香港城市大学 |
在读博士生(2名):李梦雅、薛荣跃
在读硕士生(7名):梁嘉慧、林欣颖、王宏宇、陈杉、周磊、张耀升、杨金蕾