Zhang  Xu-Xiang
 
     
 
     
     
 

 

Xu-Xiang Zhang, PhD & Associate Professor

State Key Laboratory of Pollution Control and Resource Reuse
School of the Environment
Nanjing University
Nanjing 210093
P. R. China
Tel: 86 - 25 -83595995
Fax: 86 - 25 - 83595995
Email: zhangxx@nju.edu.cn

Education

Sept. 2001 - June 2006: School of the Environment, Nanjing University (China), PhD

Sept. 1997 - Jul. 2001: Department of Biology, Anhui Normal University (China), BSc

Employment

Jan. 2010 – current: Associate Professor, School of the Environment, Nanjing    University, China

Jul. 2006 – Dec. 2009: Assistant Professor, School of the Environment, Nanjing    University, China

May 2008 - Nov. 2008: Research Associate, Department of Civil Engineering, The University of Hong Kong, Hong Kong, China

Teaching Experience

Environmental Biotechnology (for undergraduate students)

Experimental Manipulation for Environmental Biotechnology (for undergraduate students)

Research Interests

ü        Environmental biotechnology: Screening, construction and optimization of functional microorganisms for industrial wastewater and drinking water treatment.

ü        Environmental microbiology: Antibiotic resistant bacteria and resistance genes in water environment

ü        Environmental toxicology: Public health risk associated with industrial wastewater and contaminated source water

Research grants

As Principal Investigator

Jan. 2010 – Dec. 2012: Distribution, transfer and degradation of integron - gene cassette system characterized as microbial multiple resistance in water environments. Supported by Specialized Research Fund for the Doctoral Program of Higher Education (China). No. 20090091120008.

Jul. 2009 – Dec. 2011: Optimization of community structure of functional strains in advanced drinking water treatment system. Supported by Natural Science Foundation of Jiangsu Province (China). No. BK2009249.

Mar. 2009 – Sept. 2009. Technological development for design and optimization of wastewater treatment processes. Supported by GCL Engineering Limited, P. R. China.

June 2008 – May 2010: Proteomic analysis on functional strains used for biodegradation of toxic organic pollutants in source water. Supported by Science Foundation of SKL-PCRR (China). No. 2008012.

Mar. 2007 - Feb. 2010: Influence of different operational conditions on microbial community structure of the biofilters for drinking water treatment. Supported by International Foundation for Science. No. W/4215-1

Jul. 2006 – June 2008: Construction of functional strain for biodegradation of toxic organic pollutants in drinking source water. Supported by Scientific Research Startup Foundation for Talent Recruitment of Nanjing University. No. 021122410108.

As Co-Investigator

June 2008 – May 2012: Toxicological effects and health risks of secondary pollutants produced by algae bloom. Supported by the National Basic Research Program (973) of China. No. 2008CB418102.

Jan. 2005 - Dec. 2007: Regulation and optimization of biological treatment for pharmaceutical wastewater with functional strain. Supported by Science & Technology Foundation for Environmental Protection of Jiangsu Province, P. R. China. No. 2005001-1.

Jan. 2003 - Dec. 2005: Detection for molecular genetic toxicology induced by terephthalic acid and its manufacturing wastewater. Supported by PhD Program Foundation of Education Ministry, China. No. 20030284038.

Nov. 2002 - Oct. 2005: Biological treatment of petrochemical wastewater with functional strain Fhhh constructed by protoplast fusion. Supported by Hi-Tech Research and Development Program (863) of China. No. 2001AA214191.

Accomplishments and Honors

Nov. 2009, 3rd Winner, Sci-Tech Progress Award (Ⅱ) of China Associate for Instrumental Analysis, P. R. China.

Sept. 2008, 3rd Winner, Sci-Tech Progress Award (Ⅱ) of China Petroleum and Chemical Industrial Association, P. R. China.

Oct. 2006, 3rd Winner, National Sci-Tech Progress Award (Ⅲ) of Environmental Protection, P. R. China.

Selected Publications

1.        Zhang X.X., Zhang Z.Y., Ma L.P., Liu N., Wu B., Zhang Y., Li A.M.., Cheng S.P. (2010) Influeces of hydraulic loading rate on SVOCs removal and microbial community structure in drinking water treatment biofilters. Journal of Hazardous Materials, 178:652-657.

2.        Zhang X.X., Sun S.L., Zhang Y., Wu B., Zhang Z.Y., Liu B., Yang L.Y., Cheng S.P. (2010) Toxicity of purified terephthalic acid manufacturing wastewater on reproductive system of male mice (Mus musculus). Journal of Hazardous Materials, Journal of Hazardous Materials 176:300-305.

3.        Zhang X.L., Zhang Z.Y., Zhang X.X., Wu B., Zhang Y., L.Y. Yang, Cheng S.P. (2010) Effects of Yangtze River source water on genomic polymorphisms of male mice detected by RAPD. Human & Experimental Toxicology, 29(2) 113–120. (as corresponding author)

4.        Wu B., Zhang Y., Zhang X.X., Cheng S.P. (2010) Health risk analysis from exposure of organic pollutants through drinking water consumption in Nanjing, China. Bulletin of Environmental Contamination and Toxicology, 84(1):46-50.

5.        Zhang X.X., Wu B., Zhang Y., Zhang T., Yang L.Y., Fang H.H.P., Cheng S.P. (2009) Class 1 integronase gene and tetracycline resistance genes tetA and tetC in different water environments of Jiangsu Province, China. Ecotoxicology, 18:652-660.

6.        Zhang X.X., Zhang T., Zhang M., Fang H.H.P., Cheng S.P. (2009) Characterization and quantification of class 1 integrons and associated gene cassettes in sewage treatment plants. Applied Microbiology and Biotechnology, 82(6):1169-1177.

7.        Zhang X.X., Zhang T., Fang H.H.P. (2009) Antibiotic resistance genes in water environment. Applied Microbiology and Biotechnology, 82:397414.

8.        Zhang X.X., Jia H.Y., Wu B., Zhao D.Y., Li W.X., Cheng S.P. (2009) Genetic analysis of protoplast fusant Xhhh constructed for pharmaceutical wastewater treatment. Bioresource Technology, 100:1910-1914.

9.        Zhang X.X., Zhao D.Y., Wang Z.X., Wu B., Li W.X., Cheng S.P. (2009) Environmental biological model-based optimization of activated sludge process. International Journal of Environmental Science and Technology, 6(1):69-76.

10.    Sun S.L., Wu B., Zhao D.Y., Zhang Y., Zhang X.X., Li W.X., Cheng S.P. (2009) Optimization of Xhhh strain biodegradation with metal ions for pharmaceutical wastewater treatment. Journal of Environmental Biology, 30(5):877-882. (as corresponding author)

11.    Wu B., Cheng S.P., Li Y.Q., Kong J., Zhao D.Y., Zhang Y., Zhang X.X. (2009) Transcriptional toxicity of the Yangtze River source water on mouse (Mus musculus) detected by cDNA microarray. Ecotoxicology, 18:715–721. (as corresponding author)

12.    Wu B., Zhang X.X., Zhang Y., Zhao D.Y., Cui Y.B., Cheng S.P. (2009) Extracellular proteomic analysis for degradation of PAHs in source of drinking water with fusant strains. Ecotoxicology, 18:736–741.

13.    Wu B., Zhang X.X., Zhang X.L., Yasun A.S.J., Zhang Y., Zhao D.Y., Ford T., Cheng S.P. (2009) Semi-volatile organic compounds and trace elements in the Yangtze River source of drinking water. Ecotoxicology, 18:707–714.

14.    Zhang Y., Zhang X.X., Wu B., Zhao D.Y., Li M., Cui Y.B., Ford T., Cheng S.P. (2009) Degradation of benzo(a)pyrene in Yangtze River source water with functional strains. Ecotoxicology, 18:742–747.

15.    Zhang T., Zhang M., Zhang X.X., Fang H.H.P. (2009) Tetracycline resistance genes and tetracycline resistant lactose-fermenting Enterobacteriaceae in activated sludge of sewage treatment plants. Environmental Science and Technology, 43(10):3455-3460.

16.    Zhao D.Y., Wu B., Zhang Y., Jia H.Y., Zhang X.X., Cheng S.P. (2009) Identification of protoplast fusion strain Fhhh by randomly amplified polymorphic DNA. World Journal of Microbiology and Biotechnology, 25:1181-1188.

17.    Wu B., Zhao D.Y., Jia H.Y., Zhang Y., Zhang X.X., Cheng S.P. (2009) Preliminary risk assessment of trace metal pollution in surface water from Yangtze River in Nanjing Section, China. Bulletin of Environmental Contamination and Toxicology, 82:405-409.

18.    Wu B., Zhao D.Y., Zhang Y., Zhang X.X., Cheng S.P. (2009) Multivariate statistical study of organic pollutants in Nanjing reach of Yangtze River. Journal of Hazardous Materials, 169:1093-1098.

19.    Wu B., Zhang Y., Zhao D.Y., Zhang X.X., Kong Z.M., Cheng S.P. (2009) Gene expression profiles in liver of mouse after chronic exposure to drinking water. Journal of Applied Toxicology, 29(7):569-77.  

20.    Wu B., Zhang Y., Kong J., Zhang X.X., Cheng S.P. (2009) In silico predication of nuclear hormone receptors for organic pollutants by homology modeling and molecular docking. Toxicological Letters, 191: 69-73.

21.    Li W.X., Zhang X.X., Wu B., Sun S.L., Chen Y.S., Pan W.Y., Zhao D.Y., Cheng S.P. (2008). A comparative analysis of environmental quality assessment methods used for heavy metal-contaminated soils. Pedosphere, 18(3):344-352. (as corresponding author)

22.    Zhao D.Y., Zhu C.J., Sun S.L., Yu H.F., Zhang L., Pan W.Y., Zhang X.X., Cheng S.P. (2007). Toxicity of pharmaceutical wastewater on male reproductive system of Mus musculus. Toxicology and Industrial Health, 23:47-54.

23.    Zhang X.X., Cheng S.P., Sun S.L., Zhu C.J., Zhao D.Y., Pan W.Y. (2006). A pilot study on the biological treatment of PTA wastewater with functional strain Fhhh. Environmental Engineering Science, 23(6):1065-1072.

24.    Zhang X.X., Cheng S.P., Wan Y.Q., Sun S.L., Zhu C.J., Zhao D.Y., Pan W.Y. (2006). Degradability of five aromatic compounds in a pilot wastewater treatment system. International Biodeterioration & Biodegradation, 58: 94-98.

25.    Zhang X.X., Cheng S.P., Sun S.L., Zhu C. J. (2006). Microbial PAH-degradation in soil: Degradation pathways and affecting factors. Pedosphere, 16(5): 555-565.

26.    Zhu C.J., Cheng S.P., Zhang X.X., Lang Y.Z., Sun S.L., Gu J.D., Zhao D.Y., Pan W.Y., Yu H.X. (2006) PTA wastewater molecular toxicity detected with gene chip. Journal of Environmental Sciences, 18(3):514-518.

27.    Zhang X.X., Wan Y.Q., Cheng S.P., Sun S.L., Zhu C.J. (2005). Purified terephthalic acid wastewater biodegradation and toxicity. Journal of Environmental Sciences, 17 (5), 705-710.

28.    Sun S.L., Cheng S.P., Wan Y.Q., Zhang X.X., Shi L., Zhu C.J., Yu H.X. (2005). Pilot regulation of MnP level to treat PTA wastewater. Journal of Environmental Sciences, 17(3):375-378.

29.    Cheng S.P., Shi L., Zhang X.X., Yan J., Ding Z.H., Hao C.B. (2004). Prediction of Fhhh potential in PTA wastewater treatment. Journal of Environmental Sciences, 16(1):1-4.

30.    Yan J., Cheng S.P., Hao C.B., Zhang X.X., Shi L. (2004). Effect of four metal elements on the degradation of PTA wastewater for Phanaerochete chrysoporium and Fhhh. Bulletin of Environmental Contamination and Toxicology, 72:387-393.

Invention Patents of China

Zhang X.X., Li W.X., Pan W.Y., Sun S.L., Zhao D.Y., Wu B., Jia H.Y., Cheng S.P.  (2010). An informatics method used to optimize biological wastewater treatment system. Authorization No. ZL200710020122.7.

Cheng S.P., Yan J., Shi L., Zhang X.X., Hao C.B., Que Z.L., Chen J., Gu J.-D., Li W.X., Huang Q.M., Yu H.X. (2009). Methods of functional strain production and biological treatment for chemical wastewater and traditional organic wastewater. Authorization No. ZL021381712.

Cheng S.P., Sun S.L., Zhang X.X., Zhang L., Zhu C.J., Wei G.Z., Yu H.F., Wan Y.Q., Li W.X., Yu H.X. Sun C., Gu J.-D. (2006). A biological technique for pharmaceutical wastewater treatment with functional strain. Authorization No. ZL 200410041126.X.